MiXCR is a powerful software platform designed for immune profiling using NGS data. Widely adopted by major pharmaceutical companies, it supports R&D in vaccine development, antibody discovery, and cancer immunotherapy. MiXCR offers a comprehensive analytical pipeline that starts from raw sequencing data and leads to detailed biological insights.
MiXCR is highly versatile and compatible with a range of protocols and data types, including amplicon sequencing (with or without molecular barcodes), RNA-Seq, single-cell technologies, and custom protocols. With built-in presets for popular commercial kits, it simplifies complex analysis, making it possible to execute the entire pipeline with a single command.
Key Features of MiXCR
Repertoire Overlap Analysis: Provides tools to analyze overlaps between immune repertoires across samples or conditions.
End-to-End Analytical Pipeline: Analyzes raw sequencing data all the way to biological insights with a streamlined workflow.
Protocol Flexibility: Works with multiple sequencing protocols, including target amplicon, RNA-Seq, and single-cell technologies.
Preconfigured Presets: Includes ready-to-use presets for popular sequencing kits (e.g., 10x Genomics, Takara Bio) and standard public protocols.
Data Normalization: Ensures accurate, comparable results by standardizing data across experiments.
Allelic Variant Inference: Detects novel allelic variants for deeper genetic insights.
B Cell Lineage Reconstruction: Tracks lineage relationships in B cells, valuable for antibody research.
Repertoire Profiling: Generates detailed immune repertoire profiles, supporting vaccine and antibody research.
